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Charleston, SC 2+ Bedroom Vacation Rentals

1142 rentals found

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in handsome downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
The Jessamine | Charming 4BR - Ideal for...

Summary:Welcome to The Jessamine, a gorgeously styled four-bedroom home ideal for groups seeking comfort, space, and memorable time together. Located in a welcoming Charleston neighborhood, this getaway blends modern touches with thoughtful design...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 9
30-Day Marshfront Rental Condo w/Amazing...

2436 Stono Watch - 30 Day RentalOur calendar is refreshed in real-time & our nightly prices are accurately displayed. Simply enter your desired dates and click 'Book Now!'Find an incredibly serene, marshfront setting at this two-bedroom condo on...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Relax in this Cozy Property Located Clos...
5.0
(6)

Appreciate your stay in Charleston at this comfortable, and centrally-located duplex. You'll adore the striking, historic neighborhood with hundred-year-old oaks, and how quickly you can hop to downtown (3 mins.) and the beach (15 min). You'll be...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Private Balcony, 2 Living Rooms, 2 Block...
5.0
(3)

Welcome to Azaleas on Spring – Suite B!Notable amenities include:- Balcony overlooking historic Spring St- 2 Blocks to King St – Walk to Charleston’s Finest Dining, Shopping & Nightlife- Bonus second Living Room- Street Parking for 1 Car- Cozy...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Perfect Location - King Street Condo!

Summary:Welcome to your downtown Charleston escape, charmingly located just off King Street and offering both elevated vistas and shared outdoor spaces to soak up the city’s ambiance. Ideal for couples or modest groups who value comfort, design...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
Enviable Location Blending Charm and Com...
4.9
(39)

One of four residences in this 1870s-era historic refreshed property, the 2,700-square-foot "Sail Loft" residence features unique architectural details like cathedral ceilings and exposed beams, on-site exclusive parking, 3 bedrooms, 2 full...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
60' Sailing Yacht on a Private Dock
5.0
(11)

There's simply nothing else like it in Charleston!300 yards down a private road and you're in the middle of the beautiful marsh. Just you, dolphins, birds, the occasional kayaker...and of course this big sailing yacht. The three well-appointed...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
The Jacob Rabb House -Steps to the Histo...

Summary:The Jacob Rabb House (circa 1851) is located in the exclusive Ansonborough neighborhood in the heart of the Historic District. Its location presents a walkable opportunity to experience Charleston, while also providing 3 off-street parking...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
1 Block to King St | Plunge Pool | Sleep...

Summary:Feel luxury at The Pink Palm, a impressive new construction 4-bedroom, 4-bathroom getaway in downtown Charleston finished in APR 2025. Appreciate roomy living areas, chic baths, and a completely equipped kitchen. Unwind in the private plunge...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Plantation row

If your looking to discover history and life as it was 100s of years ago you can visit the three local plantations mins. from our2 bedroom suite. Also beaches and historic downtown charleston to name a few local attractions. Travellers will have...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Charleston 2 BR presidential with balcon...

This handsome boutique property blends modern lines with traditional architectural elements unique to Charleston, South Carolina, one of America’s most striking cities. King 583 offers a range of well-appointed accommodations, a very comfortable...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
New Charleston meets Old Charleston!
5.0
(1)

https://youtu.be/yoy7_cTP81w Video Link to U-tube PageFirst time on the Vacation Rental By Owner market! This beautiful monthly rental home is located in the French Quarter in a rather residential area called the Exchange, for its proximity to...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Charm of Charleston - 2 Blocks to King S...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in handsome downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
8BR Downtown Luxury Escape Near King

Summary:Ideal for sizable groups, this 8BR/8BA Charleston duplex offers two connected units with identical layouts, each with modern kitchens, beautiful living areas, and Intelligent TVs. Savor luxury linens, high-speed WiFi, and two off-street...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 18
Perfect Location - King Street Condo!

Summary:Welcome to your downtown Charleston escape, charmingly located just off King Street and offering both elevated vistas and shared outdoor spaces to soak up the city’s ambiance. Ideal for couples or modest groups who value comfort, design...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
Southern Sweetgrass the Heart of Charles...

Summary:Escape to this appealing 1810 historic two-story condo in the heart of Charleston, just one block from King Street. Featuring 3 cavernous bedrooms and 3 full bathrooms, this charmingly preserved residence blends timeless character with...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 10