Charleston, SC 2+ Bedroom Vacation Rentals

East 46 - H is a roomy three-story, 3-bedroom, 3-bathroom apartment located just one block off King Street in Charleston's vibrant Cannonborough/Elliotborough neighborhood. Appreciate painless access to local eateries, stores, and coffee stores. The...

Permit Number: 06191The Space: Welcome to The Bee and Blossom, a gorgeously reimagined historic 6-bedroom, 6.5-bath home in the laid-back Radcliffborough neighborhood, thoughtfully designed for groups of up to twelve guests!Spanning three cavernous...

DOWNTOWN- LARGE 5BR, 3BA, 5 Fireplaces, French Doors, Generous Balcony. Handsomely restored building. Very Romantic and Elegant Five Bedroom, Three Bath, Sleeps 10 people in beds, 1 to 2 on couch, 12’ Ceilings, Five Fireplaces, Sizable Pocket...

Summary:Bowen VillageThe Space:Welcome to your freshly refreshed beautiful 3-bedroom, 2-bath guest suite located in the heart of the vibrant, walkable village of Bowen! Appreciate the ideal blend of luxury and convenience, just steps away from an...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

Welcome to 1185 King Street Unit B! Located on a corner lot, this top floor, 3/2 unit is part of a enormous brick duplex located in the North Central neighborhood of downtown Charleston. Close proximity to notable dining, bars, Hampton Park and...

Permit Number: 06354The Space: Welcome to Casa Fuego, a handsomely modernized getaway occupying the second and third floors of a classic Charleston Single home, offering space, appeal, and a lively downtown location just off Spring Street!Bedrooms ...

Sleeps up to 16! This modern, freshly refreshed home consists of 2 sizable apartments, rentable separately or together. You have a private backyard to relax/dine with a wide umbrella. Wood floors sit beneath exposed beams, w/ stainless steel...

Permit Number: 06980The Space: Step into The Lady Banks House, a delightfully modernized two-bedroom getaway where historic appeal meets modern comfort in the heart of Charleston!This inviting home blends extravagant design with comfortable...

Permit Number: 06838The Space: Welcome to Palmetto House, a charmingly restored Charleston home where historic appeal meets modern comfort. With four inviting bedrooms and thoughtful gathering spaces throughout, this home is ideal for families or...

Summary:Welcome to the Barbados House, part of The Preserve, a luxury single-style home located in the heart of downtown Charleston. This elegant 5-bedroom, 5.5-bath residence offers an unparalleled blend of sophisticated appeal and modern comfort...

Charming Stay in Charleston SCBRAND NEW Single Family Home with private parking. Four blocks from King street! Just mins. from the College of Charleston, major medical centers, and the historic district. Whether you're here for business, a college...

Summary:Feel the ultimate gathering place in the heart of Charleston with our whole home TAKEOVER. This historic 1885 home offers two unique units. With nearly 3000 sq. ft. of space, you'll have plenty of room to spread out and create lasting...

Summary:Conveniently located on James Island, 5 miles from Folly Beach and Downtown Charleston, this lush live oak property features 3 separate units that share a roomy backyard. The individual units provide plenty of space for privacy with 1 king...

PLEASE NOTE: This home is the main home on the property. The home is attached to a separate garage suite that WILL BE OCCUPIED by others during your stay. However, please be assured that guests will have private and full access to the home.Welcome...

Welcome to Saint Philip Square, an award-winning collection of historic homes spanning nearly one city block of downtown Charleston. The Alexander Wilson House at 178 Unit B Saint Philip St. is a 2-bed 2-bath gem blending modern comfort with...

Summary:OP2025-05857Blue Cottage is your private and intimate Casa Zoë sanctuary with history in its bones and style in its soul. Tucked on Charleston's most coveted block, this stand-alone bungalow offers the rare blend of total privacy and...

Summary:Welcome to your Charleston getaway, a bright and modern 2-bedroom condo set in the heart of the city’s thriving Upper King corridor. Ideal for couples, friends, or modest groups, this home places you steps from the city’s most vibrant...