Isle of Palms, SC 5+ Bedroom Vacation Rentals

** During the summer we book Saturday to Saturday. Off-season we require a 3 nighttime minimum **-- Description --'Villa del Mare' is an ocean view Mediterranean masterpiece and is located just a few steps from the beach. On the relaxing Isle of...

Welcome to #32 - 41st Ave! This cavernous, refreshed five-bedroom beach home has a modern look, comfortable feel, and is ideal for your family to savor a beach vacation! Property Highlights- 3 Living Areas - All with Intelligent TVs- Free High Speed...

3205 Palm Boulevard Meet your new favorite vacation home, Atlantic Breezes on 3205 Palm Boulevard! This amazing 5-bedroom, 4.5-bathroom home is located just across Palm Boulevard from the beach, with a pretty private pool and play set in the...

Will-o-LayneLocation: Isle of Palms, South CarolinaOverview:Welcome to Will-o-Layne, a handsome and roomy 5-bedroom, 3-bathroom family beach bungalow located directly across from the ocean on the Isle of Palms. This striking home offers the ideal...

Welcome to 2905 Palm Boulevard! Located on the beautiful ocean-side of the Isle of Palms, a classic beach town near historic Charleston, South Carolina, this impressive home was FULLY REBUILT IN 2024 and expanded to 6 roomy bedrooms - all with...

This handsome 6 bedroom/6 bathroom home is located in an ideal location on the island: one block from the ocean with a direct beach access path, a short distance to the IOP Marina, and walking distance to the Citadel beach home. The peaceful...

311 Carolina Boulevard is really a rare find with ocean vistas, private pool, four roomy decks, and amazing amenities to meet your every vacation wish. Step into your vacation dream that features five bedrooms, each with a king bed, four full baths...

Introducing 58 Grandiose Pavilion, your unparalleled luxury escape in the heart of Wild Dunes. This gorgeous oceanfront getaway, completely remodeled in 2023, offers 6 bedrooms and 6.5 bathrooms across 3,900 square feet of pure elegance.Step inside...

Book June 13-20, 2026 and receive a complimentary golf cart rental for the week! BR 1: King, BR 2: King, BR 3: King BR 4: King, BR 5: King, BR 6: King, BR 7: King, BR 8: 2 Queens, BR 9: 2 Twin, BR 10: 2 Twin; Sleeps 22, Near Beach, Private Pool...

Bikinis and MartinisLocation: Isle of Palms, SCOverview:Welcome to Bikinis and Martinis, a gorgeous 5-bedroom, 5.5-bathroom new construction home located just a block from the beach on Isle of Palms. This luxury getaway offers an open-concept design...

16 29th Avenue blends coastal appeal and modern comfort for the ideal Isle of Palms getaway. Set about 3 blocks from the beach—just a leisurely 4-min. walk—this home places you within painless reach of sun-soaked shores and the lively Isle of...

Tucked into the peaceful north end of Isle of Palms, 3602 Cameron is the kind of beach home that makes you slow down the second you walk in. The ocean is essentially across the street — Beach Access 34A sits just steps from the front door, so...

The Eleanor House – Modern Elegance with Private Pool & Coastal CharmWelcome to The Eleanor House, a striking new build on Isle of Palms offering the ideal blend of refined coastal design and effortless vacation comfort. Just a 5-min. walk to the...

Welcome to 10 Yacht Harbor, your dream hideaway in Wild Dunes Resort on the pretty Isle of Palms. This newly constructed 5-bedroom vacation rental combines opulent comfort with the casual appeal of southern coastal living. Just a short 25-min. drive...

The Rosemary House – Modern Elegance Meets Island CharmWelcome to The Rosemary House, a beautiful and sun-soaked getaway located just behind the gates of Wild Dunes Resort and mere steps from the pristine sands of Isle of Palms. This freshly...

Incredible 5 Bedroom, 4.5 bath home with new elevated Salt Water Pool, fresh furnishings and coastal décor. Executive Kitchen with Sub Zero, Wolf and Bosch appliances completely equipped for the cooks on vacation. The dining Room seats 8 with room...

6 54th Ave | Blue HavenIsle of Palms, SCOverview:Welcome to "Blue Haven," a spectacular 5 bedroom and 5 ½ bath home with a pool and ocean vistas. This huge home has 2 broad living rooms and each have access to a roomy veranda with comfortable...

Welcome to 9 22nd Avenue, a striking luxury getaway on the Isle of Palms where casual coastal living meets high-end design. Just steps from the sand, this six-bedroom, four-and-a-half-bath home offers the ideal balance of sophistication and...