Isle of Palms, SC 5+ Bedroom Vacation Rentals
- Atlantic Beach
- Avon
- Bald Head Island
- Beaufort
- Beaufort
- Buxton
- Carolina Beach
- Carova
- Charleston
- Corolla
- Duck
- Elizabeth City
- Emerald Isle
- Fripp Island
- Frisco
- Georgetown
- Grandy
- Hatteras
- Hilton Head
- Holden Beach
- Indian Beach
- Isle of Palms
- Jarvisburg
- Kill Devil Hills
- Kitty Hawk
- Kure Beach
- Manteo
- Myrtle Beach
- Nags Head
- New Bern
- Oak Island
- Ocean Isle Beach
- Ocracoke
- Pine Knoll Shores
- Point Harbor
- Poplar Branch
- Port Royal
- Powells Point
- Rodanthe
- Salvo
- Southern Shores
- Southport
- Sullivans Island
- Sunset Beach
- Wanchese
- Waves
- Wilmington
- Wrightsville Beach
This splendid 6 bedroom, 6.5 bathroom home is ready to welcome you for a once-in-a-lifetime beach escape. Just one block to the beach, it has all you need to make phenomenal memories on the Isle of Palms. It features two living rooms, a entirely...
- Isle of Palms
- 6 Bedrooms
- 6 Bathrooms
- Sleeps 12
Welcome to your Isle of Palms escape at 3806 Cameron Boulevard—a impressive 6-bedroom coastal getaway designed for memorable beach vacations with family and friends.Located on the 3rd row of homes on the island and just steps from the sand, this...
- Isle of Palms
- 6 Bedrooms
- 6 Bathrooms
- Sleeps 14
Fishers Alley 5 by Wild Dunes6 Bedrooms | 6 Bathrooms | Sleeps 12 | Reserve________________________________________Welcome to Fishers Alley 5, a impressive getaway on Isle of Palms’ exclusive Wild Dunes Resort. Just a block and a half from the...
- Isle of Palms
- 6 Bedrooms
- 6 Bathrooms
- Sleeps 12
*Planning a winter beach escape? Stay in January or February 2027 and you can heat the pool for COMPLIMENTARY!*Introducing THE PEARL, one of our premier properties on the Isle of Palms! This roomy Charleston-style home was refreshed in early 2024...
- Isle of Palms
- 7 Bedrooms
- 7 Bathrooms
- Sleeps 20
Welcome to 3108 Palm by AvantStay!Welcome to 3108 Palm, your oceanfront sanctuary on the Isle of Palms. This beach villa beckons with a private boardwalk leading you directly to the shore, ensuring countless moments of oceanside bliss.Dip into...
- Isle of Palms
- 6 Bedrooms
- 7 Bathrooms
- Sleeps 12
Welcome to 10 Yacht Harbor, your dream hideaway in Wild Dunes Resort on the impressive Isle of Palms. This newly constructed 5-bedroom vacation rental combines opulent comfort with the casual appeal of southern coastal living. Just a short 25-min...
- Isle of Palms
- 5 Bedrooms
- 4 Bathrooms
- Sleeps 12
**Summer bookings are Sat. to Sat. We have a 3 nighttime min in the off-season** Description"Isle be Back" - 5 57th Avenue is one of our newest additions. It is a pretty, six bedroom, five and a half bathroom inverted floor plan home with...
- Isle of Palms
- 6 Bedrooms
- 5 Bathrooms
- Sleeps 16
Introducing 58 Grandiose Pavilion, your unparalleled luxury escape in the heart of Wild Dunes. This gorgeous oceanfront getaway, entirely remodeled in 2023, offers 6 bedrooms and 6.5 bathrooms across 3,900 square feet of pure elegance.Step inside...
- Isle of Palms
- 6 Bedrooms
- 6 Bathrooms
- Sleeps 12
Welcome to Sand Dune. Heaven beckons from this marvelous beach home that's located only 1 block away from the sandy shores of Isle of Palms Beach. Recently remodeled in 2025, Sand Dune now features major upgrades to the kitchen and bathrooms...
- Isle of Palms
- 6 Bedrooms
- 4 Bathrooms
- Sleeps 12
Brand new to the rental program! Remodeled in 2024 with all rooms freshly painted, refinished wood floors throughout, and a new kitchen. Incredible 5 Bedroom vacation home in the exclusive gated Ocean Point Community of Wild Dunes Resort. Access to...
- Isle of Palms
- 5 Bedrooms
- 4 Bathrooms
- Sleeps 10
Ever wonder what a true resort beach vacation near Charleston would be like? Then it's time to experience "LIVIN' ON A DUNE"!Located in the heart of Wild Dunes Resort on the Isle of Palms and just a block away from the pristine beach, this...
- Isle of Palms
- 5 Bedrooms
- 3 Bathrooms
- Sleeps 10
Only a brief walk from the pristine sandy beach, this striking 6-bedroom, 4.5-bathroom coastal getaway offers the ideal blend of relaxation, style, and convenience. Designed with families and groups in mind, this Isle of Palms vacation home is your...
- Isle of Palms
- 6 Bedrooms
- 4 Bathrooms
- Sleeps 14
Snowbirds Welcome!!Winter Escape to IOP.....Property Description Discover the pinnacle of luxury beach living at this exquisitely designed beach home, located in the heart of Isle of Palms, South Carolina. This impeccable getaway blends coastal...
- Isle of Palms
- 5 Bedrooms
- 4 Bathrooms
- Sleeps 12
6 54th Ave | Blue HavenIsle of Palms, SCOverview:Welcome to "Blue Haven," a spectacular 5 bedroom and 5 ½ bath home with a pool and ocean vistas. This huge home has 2 broad living rooms and each have access to a cavernous veranda with comfortable...
- Isle of Palms
- 5 Bedrooms
- 5 Bathrooms
- Sleeps 12
Welcome to Casa Flamingo! Presented by Exclusive Properties on Isle of Palms. *Plug in your dates to see the full quote! Email us with any questions regarding the home or the quote or discounts. **Available all year! During the Summer months...
- Isle of Palms
- 8 Bedrooms
- 6 Bathrooms
- Sleeps 19
Isle of Palms Getaway – Pool, Beach, Dining & Fun Right Outside Your Door!Everything you need for the ideal beach vacation is right at your fingertips! This elegant Isle of Palms home sleeps up to 14 guests, with 7 roomy bedrooms and 5 full...
- Isle of Palms
- 7 Bedrooms
- 5 Bathrooms
- Sleeps 14
Casa TortugaLocation: Isle of Palms, South CarolinaOverview:Welcome to Casa Tortuga, a extravagant 5-bedroom, 5.5-bathroom island getaway designed for the ultimate family vacation. Located on the gorgeous Isle of Palms, this modern home features a...
- Isle of Palms
- 5 Bedrooms
- 5 Bathrooms
- Sleeps 12
For those looking to experience a true oceanfront beach vacation on the Isle of Palms, this handsome 5 bedroom home located along beautiful Palm Boulevard is the ideal spot for your next beachfront island hideaway! This home offers striking ocean...
- Isle of Palms
- 5 Bedrooms
- 4 Bathrooms
- Sleeps 12