Isle of Palms, SC 4+ Bedroom Vacation Rentals

Cruise down Palm Blvd to find the most ideal beach vacation home, ideal for a family hideaway to Isle of Palms! This 5-bedroom, 4-bathroom home is the quintessential oceanfront escape, and offers an superb location close to island eateries and...

Welcome to your ideal coastal getaway at 28 Pelican Bay! This impressive and inviting 4-bedroom beach home is located in a calming, oceanside neighborhood, just a leisurely 3–4 min. walk from the pristine shoreline. Ideal for families, this home...

**Summer bookings are Sat. to Sat. We have a 3 nighttime min in the off-season** Description"Isle be Back" - 5 57th Avenue is one of our newest additions. It is a handsome, six bedroom, five and a half bathroom inverted floor plan home with...

The Olivia House – Coastal Elegance Inside the Gates of Wild DunesTucked just behind the gates of Wild Dunes Resort and only a short walk from the sun-kissed sands of Isle of Palms, The Olivia House offers the ideal setting for your next...

Incredible 5 Bedroom, 4.5 bath home with new elevated Salt Water Pool, fresh furnishings and coastal décor. Executive Kitchen with Sub Zero, Wolf and Bosch appliances entirely equipped for the cooks on vacation. The dining Room seats 8 with room...

Ask about our discounts for Spring/Summer 2026!Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of Palms. We specialize in...

Snowbirds Welcome!!Winter Escape to IOP.....Property Description Discover the pinnacle of luxury beach living at this exquisitely designed beach home, located in the heart of Isle of Palms, South Carolina. This impeccable getaway blends coastal...

** During the summer we book Friday to Friday. Off-season we require a 3 nighttime minimum **--Description--'Coastal Manor' is a brand new bespoke constructed home located on Palm Blvd. right across from the ocean with a convenient beach access just...

Welcome to 118 Charleston IOP Beachhouse by AvantStay!Tucked along one of Isle of Palms’ most beloved beach corridors, this broad coastal getaway pairs easygoing Charleston appeal with effortless access to sand and surf. Just steps from a beach...

The Laurel House – Secluded Elegance, Steps from the BeachWelcome to The Laurel House, a 4-bedroom, 4-bath coastal getaway that blends spa-like serenity with classic beachside appeal. Located just 100 yards from the ocean, and surrounded by...

Amazing luxury rental located on a peaceful street just a few steps to the beach boardwalk. Loaded with outdoor amenities including an broad backyard complete private pool, chaise loungers, and outdoor shower. Appreciate vistas of the ocean from the...

White SandsLocation: Isle of Palms, South CarolinaOverview:Welcome to White Sands, a attractively refreshed 4-bedroom, 4.5-bathroom coastal getaway on Palm Boulevard. Professionally designed with high-end finishes, this delightful home offers luxury...

**2204 Palm Blvd is Presented by Exclusive Properties Vacation Rental Agency on Isle of Palms** Ask about our Spring/Summer 2026 discounts! --Description--'Avonlea' -2204 Palm Blvd,is a pretty bespoke constructed five bedroom, six and a half bath...

Racquet Club Villa 22 by Wild Dunes4 Bedrooms | 3 Bathrooms | Sleeps 8 | Resort View________________________________________Savor a prime 1830 Sq. Ft. location near pools, eateries, main beach access and shopping. This lively community offers both...

The Carolina House – Roomy, Pet-Friendly Coastal Comfort in Wild DunesWelcome to The Carolina House, a classic Lowcountry getaway tucked within a private, gated enclave inside the acclaimed Wild Dunes Resort on Isle of Palms. This 4-bedroom...

**We are Saturday to Saturday in the Summer, but we have a 3 nighttime min in the off-season**--Description--'Seascapes' 714 Ocean Blvd, is a classic oceanfront home located in the esteemed Ocean Blvd. side of the island which places the beach just...

Sandy CheeksLocation: 6 26th Ave Isle of Palms, SCOverview:Welcome to this entirely refreshed 6-bedroom, 3-bathroom home on the elite Isle of Palms. Ideal for families or groups, this cavernous single-family home offers opulent amenities, including...

--Description--'Beach Bliss', 3 53rd Ave, is an elegant and newly constructed masterpiece. This striking property showcases six cavernous bedrooms each adorned with 10-foot ceilings and opulent ensuite bathrooms. Located on a serene street at the...