Isle of Palms, SC 4+ Bedroom Vacation Rentals

Welcome to 9 22nd Avenue, a striking luxury getaway on the Isle of Palms where casual coastal living meets high-end design. Just steps from the sand, this six-bedroom, four-and-a-half-bath home offers the ideal balance of sophistication and...

6 54th Ave | Blue HavenIsle of Palms, SCOverview:Welcome to "Blue Haven," a spectacular 5 bedroom and 5 ½ bath home with a pool and ocean vistas. This huge home has 2 broad living rooms and each have access to a roomy veranda with comfortable...

**Summer bookings are Sat. to Sat. We have a 3 nighttime min in the off-season** Description"Isle be Back" - 5 57th Avenue is one of our newest additions. It is a charming, six bedroom, five and a half bathroom inverted floor plan home with...

Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of Palms. We specialize in handsome, luxury or budget friendly vacation...

Welcome to your vacation at the Blue House! This 4 bed, 3 bath home is freshly refreshed with all remodeled bathrooms and kitchen upgrades. Appreciate a short 2 min. walk to the beach, as this home is located just 3 homes back. A brand new Hot Tub...

2401 Palm | Will-o-LayneLocation: Isle of Palms, South Carolina Overview:Welcome to Will-o-Layne, a handsome and roomy 5-bedroom, 3-bathroom family beach bungalow located directly across from the ocean on the Isle of Palms. This beautiful home...

Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of Palms. We specialize in gorgeous, luxury or budget friendly vacation...

Welcome to 36 Grandiose Pavilion, a impressive coastal getaway ideally located in the heart of Wild Dunes Resort. This attractively appointed home offers the best of Isle of Palms living, just steps from the beach and moments from the resort's most...

Welcome to SEA'S THE DREAM! Just north of historic Charleston sits this impressive 5 bedroom home with private pool and vistas of the breathtaking Intracoastal Waterway on the Isle of Palms. It would surely be the ideal spot for your next vacation! ...

Tucked into a peaceful pocket of Isle of Palms, 55 Pelican Bay is the kind of beach home that makes you forget what day it is. Step out back and the Pelican Bay community pool is right there — an simple splash before or after beach hours. From...

Welcome to 4 Lauden Boulevard! Whether you are planning a family vacation, a friends' getaway, or an extended beach escape, this attractively refreshed 4-bedroom, 3.5-bath home offers everything you need for a really calming stay on the South...

Welcome to 118 Charleston IOP Beachhouse by AvantStay!Tucked along one of Isle of Palms’ most beloved beach corridors, this broad coastal getaway pairs easygoing Charleston appeal with effortless access to sand and surf. Just steps from a beach...

Step into unparalleled coastal luxury at this freshly constructed, professionally designed oceanfront 5-bedroom home—one of Isle of Palms' premier vacation units. Sandcastle, 2704 Palm Blvd., has every detail crafted for high-end living, from the...

3205 Palm Boulevard Meet your new favorite vacation home, Atlantic Breezes on 3205 Palm Boulevard! This magnificent 5-bedroom, 4.5-bathroom home is located just across Palm Boulevard from the beach, with a pretty private pool and play set in the...

10 Ocean Point Haven is a refined Isle of Palms escape where coastal elegance, ocean vistas, and Lowcountry ease come together. Set in the gated Ocean Point community, this 4-bedroom getaway places you moments from the beach, with access to...

5 32nd Avenue, is the ideal heading to lead you to the ideal beach vacation on the Isle of Palms at 5 on 32nd Avenue. This handsome home is modeled in a nautical theme, straight from a 1920’s racing sailing schooner. Heart of Pine floors, white...

This vacation getaway with spectacular oceanfront vistas will linger in your mind long after your vacation is over! Enter into one of only a few four-bedroom oceanfront condominiums featured in Wild Dunes, 402 Summer House! Four bedrooms, four full...

Looking for the ideal home for your next Charleston beach vacation? You found it! Welcome to Heads Carolina at 3101 Waterway, one of our most fashionable listings!Some of our favorite features:Waterway, Golf and Sunset VistasPrivate Pool with Hot...