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Charleston, SC 4+ Bedroom Vacation Rentals

342 rentals found
12 Cannon Units A & B

Welcome to 12 Cannon Street, Units A & B – a gorgeously restored 6BR/6BA home in downtown Charleston, where you can savor the best of both worlds relaxing residential living combined with simple access to Charleston's vibrant dining, shopping, and...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Spacious 4BR Retreat w/ Huge Yard, Outdo...

Roomy 4BR home (2x King, 2x Queen) just 12 mins. from Folly Beach and 8 mins. to downtown Charleston. Appreciate a humongous fenced yard, outdoor shower, fire pit, and a enormous dining table with umbrella and fan—ideal for warm evenings. Located...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Southern Stunner - 4 bedroom house close...
5.0
(4)

Welcome to the Southern Stunner. A freshly remodeled home in the highly coveted Riverland Terrace neighborhood. Savor a walk down the street and see dolphins swimming in Wappoo Creek or grab a cup of coffee and watch the boats cruise by. This...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
The Gentian House | Efficiency Meets Ele...
4.6
(12)

Permit Number: 05256The Space: This brand new 2 story home was freshly constructed and refurnished. It has a bright, fresh design and is decorated in a modern-transitional style. Our home can accommodate enormous or modest groups and is ideal for...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 11
New Build - Steps to King Street

Feel the epitome of modern Charleston living in this impressive, brand new, 5-bedroom, 5-bathroom vacation rental apartment, aptly named The Chateau. Located in the heart of downtown Charleston, this opulent abode offers an unbeatable location with...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
The Manor by Guesthouse Charleston B- Im...
5.0
(6)

91B Spring Street is a attractively restored Victorian Home. This home has 4 bedrooms and 4.5 bathrooms with a enormous open living, dining, and kitchen area that opens up to roomy front porches that overlook the piazza. Vacationing in this home...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
New! Historic Residence – Great For La...

Summary:Welcome to Emerson Square Charleston, a sizable and professionally designed residence that seamlessly blends Charleston’s rich history with modern luxury. Spanning the entire second and third floors of a meticulously restored historic...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
The Parthenon Suites | 2 Blocks to King ...

Permit Number: 05086The Space: Savor the comfort and privacy of two handsomely appointed homes, ideal for enormous groups, families, or special gatherings. Located in a relaxing neighborhood, this roomy getaway offers everything you need for a...

  • Charleston
  • 10 Bedrooms
  • 7 Bathrooms
  • Sleeps 20
Point of View | Casa Zoë - Award Winnin...
4.9
(48)

Summary:Slide into the heart of Charleston like you own the place with Casa Zoë, your VIP pass to the city’s thrumming pulse, right where the action is—on the most elite street and on the best block in the Short Term Overlay District. But...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Restored Charleston Home -- 2 Blocks fro...
4.7
(13)

Welcome to our freshly refreshed Charleston home! It is located in the charming Cannonborough-Elliotborough neighborhood only two blocks from King St. Close proximity to the areas most beautiful dining and shopping destinations. With original heart...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 15
2 Luxury Homes w/ Patios | 1 Block from ...

Summary:Discover luxury pair of completely refreshed luxury homes ideal for a enormous group, located next door to each other just moments from King St. Indulge in beautiful interiors awash with natural light from wrap-around windows. These...

  • Charleston
  • 8 Bedrooms
  • 7 Bathrooms
  • Sleeps 20
Luxurious 4BR Downtown Home - Walkable!

Summary:Welcome to "Luxurious 4BR Downtown Home - Walkable!", your ideal Charleston getaway! Located just off King Street in the Crosstown neighborhood, this striking home offers 4 elegantly appointed bedrooms, each with a private en suite bath...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 9
Carolina Rose | Southern Luxurious Escap...
5.0
(1)

Permit Number: 05056The Space: Escape to The Carolina Rose on Cannon for an unparalleled blend of luxury and comfort! ????✨ This freshly constructed gem welcomes groups of up to 8 guests, offering four lavish King Beds, each with private full...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
Downtown Charleston 8 Bedroom
4.7
(31)

Recently constructed, three-home complex, centrally located in Downtown Charleston! ✦Over 5,000 SQ FT!! ✦ Great for sizable groups - spend time together, but everybody can have their space!✦Open-air porches, welcoming living areas & roomy...

  • Charleston
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 20
6BD/6BA Downtown Home ? 2 Blocks from Ki...
5.0
(2)

Summary:Wonderful 6 bedroom/6 bathroom home in the best location in Charleston. This freshly-refreshed home is comprised of 2 3-bedroom units, each with their own living and kitchen space. Ideal for groups or multiple families!★ 2 blocks to King...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Guesthouse Charleston: SOUTH (82 A & B)
5.0
(4)

82 A & B is a cavernous two-story home, charmingly located within walking distance of Charleston's best eateries, bars, and attractions. Ideal for enormous groups, the home features two completely equipped kitchens, two living areas, and multiple...

  • Charleston
  • 8 Bedrooms
  • 9 Bathrooms
  • Sleeps 18
Luxury Downtown Home with Pool!

Step into the heart of Charleston’s historic appeal at the William Thompson House, a meticulously preserved 1843 masterpiece in downtown’s Ansonborough neighborhood. A short walk from King Street’s lively stores, eateries, MUSC, and the...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
Charleston Vacation Rental with Yard!

This beautiful Charleston vacation rental offers the ideal destination for a family getaway! Located 17 miles from Folly Beach, this home lets you savor the sun and sand before heading back to relax in front of one of 6 Intelligent TVs. The...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 6