Charleston, SC 4+ Bedroom Vacation Rentals

Summary:Discover this massive 10-bedroom, 10-bathroom getaway in downtown Charleston, accommodating up to 22 guests. Luxuriate in open living spaces, a completely equipped kitchen, and king-size beds throughout. With off-street parking, modern...

Summary:OP2025-06817Royal Cottage II is a modern-meets-historic Casa Zoë sanctuary. Designed with soul, light, and intention. Featuring four thoughtfully appointed bedrooms (each with ensuite baths), vaulted ceilings, wood floors, and...

26 Bee Street features two distinct units in Charleston's charming Cannonborough/Elliotborough neighborhood. This vibrant property includes five bedrooms and five bathrooms across both units, each delightfully restored to showcase historic appeal...

Step into Charleston’s history with this striking 4-bedroom, 4-bathroom circa-1830 home, just steps from Rainbow Row and The Battery. This fashonable getaway offers period antiques, crystal chandeliers, and grandiose piazzas, blending historic...

Summary:Feel modern luxury in historic Charleston at The Hawthorne! This brand-new 4-bed, 4-bath home is steps from King Street's vibrant energy. Ideal for groups, it features a full kitchen, private balcony, and huge comfortable living room for you...

Summary:Feel Charleston in this sophisticated 5-bedroom, 4-bath getaway designed for families or groups of friends who value comfort, space, and style. Located in a prime neighborhood, you’ll be close to vibrant dining, historic appeal, and the...

Summary:Substantial groups looking for a authentic, welcoming home away from home in downtown Charleston look no further! Our newly-refreshed historic home offers three separate 3 bedroom/3 bath units housed within the same home for a total of 9...

Summary:Welcome to Emerson Square Charleston - a huge, professionally designed residence where historic character meets modern luxury. Encompassing the entire second and third floors of a meticulously restored historic building, this broad...

Summary:Feel Charleston in this elegant 5-bed, 5-bath Victorian getaway for huge groups. Part of the exclusive Inns collection, this home is steps from King Street's famed dining and shopping. Savor modern luxury, a private balcony, and dedicated...

Permit Number: 05553The Space: Welcome to The Queen’s Palace, your private Charleston getaway made up of three delightfully restored historic homes in the heart of the Cannonborough–Elliotborough neighborhood. With eight bedrooms, eight...

1/2 Mi to Movie Theater & Dining | Suburban Neighborhood | 15 Mi to Folly BeachSwap the snow for the South Carolina sunshine! This Charleston vacation rental offers the ideal base for snowbirds and those seeking long-term accommodations. Kick off...

Summary:Welcome to the Barbados House, part of The Preserve, a luxury single-style home located in the heart of downtown Charleston. This charming 5-bedroom, 5.5-bath residence offers an unparalleled blend of sophisticated appeal and modern comfort...

Permit Number: 06948The Space: Welcome to your Charleston getaway at 11 George Street!TThis impressive and cavernous home features 5 attractively appointed bedrooms and 3 full bathrooms, making it an ideal getaway for families, friends, or bigger...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

Stunning 4 bedroom, 2 bathroom home centrally located in North Charleston. Bedroom 1: King bed, ensuite bathroomBedroom 2: King bedBedroom 3: Queen bedBedroom 4: Full/twin bunk bedAmazing home away from home!-Game room with ping pong & board...

Summary:OP2025-05862Sparrow House is a stately Federal-style, National Register residence reimagined for modern group stays. This full-home Casa Zoë gem blends historic appeal—porches, millwork, heart pine floors—with bold, gallery-worthy...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

More photos coming soon!Dive in to this freshly refreshed 6-bedroom, 5.5 bathroom home with a brand new pool, ideal for hosting up to 12 guests. This three-story haven, adorned with wood floor, original fireplaces, and high ceilings with exposed...