Isle of Palms, SC 2+ Bedroom Vacation Rentals

Welcome to Sea Shell by AvantStay!Heaven beckons from this exceptional beach home that's located only 1 block away from the sandy shores of Isle of Palms Beach. After a day spent frolicking in the waves, strolling down the boardwalk, and...

This vacation getaway with striking oceanfront vistas will linger in your mind long after your vacation is over! Enter into one of only a few four-bedroom oceanfront condominiums featured in Wild Dunes, 402 Summer House! Four bedrooms, four full...

Twin Oaks 26 by Wild Dunes3 Bedrooms | 2 Bathrooms | Sleeps 6 | Golf View________________________________________Twin Oaks enjoys a prime setting just moments from appealing stores, gourmet eateries, and the energetic center of the resort. Designed...

For those looking to experience a true oceanfront beach vacation on the Isle of Palms, this elegant 5 bedroom home located along charming Palm Boulevard is the ideal spot for your next beachfront island hideaway! This home offers handsome ocean...

Welcome to #19 on 21st Avenue on the Isle of Palms! Constructed in 2019, this striking 6 bedroom Isle of Palms home is a 3400 square foot gem! With two sizable living areas and cavernous bedrooms that comfortable sleeps 12 guests, it's ideal for...

A two-story top-floor penthouse on one of the best stretches of beach in Wild Dunes, 415B Shipwatch wraps three bedrooms, three full baths, and three private balconies around some of the widest Atlantic vistas the resort has to offer. The balconies...

Beachwood West 23 by Wild Dunes4 Bedrooms | 3 Bathrooms | Sleeps 9 | Resort View________________________________________Welcome to Beachwood West 23, a striking getaway on Isle of Palms’ exclusive Wild Dunes Resort. Located in the exclusive...

Sandy CheeksLocation: 6 26th Ave Isle of Palms, SCOverview:Welcome to this entirely refreshed 6-bedroom, 3-bathroom home on the elite Isle of Palms. Ideal for families or groups, this cavernous single-family home offers extravagant amenities...

Ask about our discounts for Spring/Summer 2026!Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of Palms. We specialize in...

Camp Carolina has a private pool and is close to the beach and Downtown Isle of Palms. This home is located on Carolina Blvd and is in a location which accepts for walking to the beach, eateries, live music and stores. The beach path is only a 2...

Check your cares at the door and settle into vacation mode at this handsome Isle of Palms hideaway! Located just two blocks from the beach and only steps from the eateries and amenities of Wild Dunes Resort, this home really offers the best of both...

This pretty 6 bedroom, 6.5 bathroom home is ready to welcome you for a once-in-a-lifetime beach escape. Just one block to the beach, it has all you need to make magnificent memories on the Isle of Palms. It features two living rooms, a completely...

Feel The Pinnacle of Coastal Luxury in this Renovated Home - 9 on 30th Ave!Property HighlightsChef's kitchen with premium appliancesPrivate saltwater pool & professional grillePutting green & fire pitRooftop deck with partial ocean vistas$250...

Welcome to 222 D Shipwatch! This gorgeously designed 2BDR condo is highlighted with a magnificent oceanfront balcony, beach access, and a community pool! The interior of 222 D Shipwatch welcomes you with a bright, beachy ambiance. Prepare...

Ocean Club 4209 by Wild Dunes3 Bedrooms | 3.5 Bathrooms | Sleeps 8 | Oceanfront________________________________________With a complex pool and unparalleled oceanfront vistas, this 2257 Sq. Ft. Ocean Club condo provides a relaxing and sophisticated...

If you're looking for a beach home with all the amenities you'll need for an memorable Isle of Palms vacation, then get ready to book your next hideaway at 3705 Cameron Blvd! This extraordinary 2-bedroom, 2-bathroom property is only a block to the...

Perched above the palm trees and looking out on the water of the Atlantic, this three bedroom, three bath Shipwatch villa offers a comfortable getaway for your Isle of Palms vacation. Savor delightful interiors, expansive vistas of the ocean and...

Casa Margarita | Oceanfront Luxury for the Ultimate Isle of Palms GetawayWelcome to Casa Margarita, an extraordinary oceanfront getaway located at 904 Ocean Boulevard. Designed for memorable family get-togethers, group vacations, and special...