Isle of Palms, SC 2+ Bedroom Vacation Rentals

Introducing THE PEARL, one of our premier properties on the Isle of Palms! This cavernous Charleston-style home was refreshed in early 2024 with wood floor throughout, remodeled first-floor kitchen space, upgraded bathrooms, as well as unbelievable...

Welcome to your ideal coastal getaway at 28 Pelican Bay! This appealing and inviting 4-bedroom beach home is located in a relaxing, oceanside neighborhood, just a leisurely 3–4 min. walk from the pristine shoreline. Ideal for families, this home...

Centrally located on the spectacular Isle of Palms just outside of historic Charleston, this striking 5-bedroom home on 22nd Avenue is the ideal place to appreciate a family beach vacation! Renovated in 2021, this home provides a modern, upgraded...

Have you been looking for your next Isle of Palms vacation rental? Well look no further than this amazing 3-bedroom, 2-bathroom family beach home that enjoys a central location off Palm Blvd, right in the heart of Isle of Palms near the public...

Welcome to 118 Charleston IOP Beachhouse by AvantStay!Tucked along one of Isle of Palms’ most beloved beach corridors, this broad coastal getaway pairs easygoing Charleston appeal with effortless access to sand and surf. Just steps from a beach...

All 2025 reservation will receive $250 credit toward beach gear units with VayK Life! *3-21 nights only2026 Beach Restoration UpdateThe City of Isle of Palms has approved a beach nourishment project planned for Summer-Fall 2026. Although the final...

Coastal breezes and sweeping resort vistas set the tone at 411 Summerhouse, a bright and inviting condo on Isle of Palms. With a private balcony overlooking the lush grounds and shining ocean beyond, this laid-back coastal getaway is designed for...

Racquet Club Villa 32 by Wild Dunes2 Bedrooms | 2 Bathrooms | Sleeps 6 | Resort View________________________________________Savor a prime 1268 Sq. Ft. location near pools, eateries, main beach access and shopping. This lively community offers both...

Welcome to 3907 Palm Boulevard, a striking 8-bedroom ocean view home on the handsome Isle of Palms, just a short drive from the historic city of Charleston. This freshly constructed residence showcases refined coastal elegance throughout, offering...

Step into the epitome of luxury and relaxation at 7 Beachwood East, a freshly constructed modern beach home located in a gated community just one lot back from the ocean. Ideal for family get-togethers or group getaways, this 7-bedroom masterpiece...

Welcome to 3108 Palm by AvantStay!Welcome to 3108 Palm, your oceanfront sanctuary on the Isle of Palms. This beach villa beckons with a private boardwalk leading you directly to the shore, ensuring countless moments of oceanside bliss.Dip into...

Choose luxury, convenience, and comfort when you look for a vacation rental at the handsome Isle of Palms. If you excited to savor this pretty beach destination with your appreciated ones, you can stay at our oceanfront home at 700 Ocean Blvd. This...

Casa TortugaLocation: Isle of Palms, South CarolinaOverview:Welcome to Casa Tortuga, a opulent 5-bedroom, 5.5-bathroom island getaway designed for the ultimate family vacation. Located on the gorgeous Isle of Palms, this modern home features a...

Only 1 block from the beach! Telephone for short stays! This gorgeous 5 bedroom home was newly refreshed. The home sits on a huge lot and has a elegant saltwater pool, outstanding screened-in back porch and breathtaking front porch. The roomy...

Dreaming of a Relaxing Getaway? Check Out This Isle of Palms Condo!Property Highlights- Inside the calming Wild Dunes Resort- Saltwater Pool and Spa (Open 4/1-10/31, weather permittiing)- Ground Level End Unit- Community Grille, Outdoor Seating Area...

Welcome to 301 Summer House Villa, a striking beachfront, oceanfront vacation rental located within the gated community of Wild Dunes Resort on the peaceful northern tip of the Isle of Palms. Just a 20-min. drive to historic Charleston, this is the...

Twin Oaks 26 by Wild Dunes3 Bedrooms | 2 Bathrooms | Sleeps 6 | Resort View________________________________________Twin Oaks enjoys a prime setting just moments from beautiful stores, gourmet eateries, and the energetic center of the resort...

Wake up to the sound of the waves at this delightfully positioned oceanfront condo in Shipwatch at Wild Dunes Resort. Ideal for a calming coastal escape, this 2-bedroom, 2-bath getaway offers front-row access to the beach along with the comfort and...