Isle of Palms, SC 2+ Bedroom Vacation Rentals

Welcome to #19 on 21st Avenue on the Isle of Palms! Constructed in 2019, this amazing 6 bedroom Isle of Palms home is a 3400 square foot gem! With two enormous living areas and roomy bedrooms that comfortable sleeps 12 guests, it's ideal for huge...

**We are Saturday to Saturday in the Summer, but we have a 3 nighttime min in the off-season**--Description--'Seascapes' 714 Ocean Blvd, is a classic oceanfront home located in the esteemed Ocean Blvd. side of the island which places the beach just...

Ask about our Spring/Summer 2026 discounts! **This home books Friday to Friday in the Summer months**--Description--Part of our luxury collection, 'Villa Las Palmas', 206 Ocean Blvd., is a seven bedroom, seven and a half bathroom oceanfront home...

Hidden among lush, tropical foliage and majestic live oaks are the elegantly landscaped Seagrove Villas. Just steps from the ocean, this modern 2 bedroom villa is the ideal place for families to reconnect or couples to getaway. Waiting for you are...

Ideal couples or modest family getaway! Freshly remodeled condo in central location on Isle of Palms. 204A Oceanside provides simple access to the Island's main strip including a variety of eateries, live music, local stores, and the county park...

Welcome to 10 Yacht Harbor, your dream hideaway in Wild Dunes Resort on the striking Isle of Palms. This newly constructed 5-bedroom vacation rental combines extravagant comfort with the casual appeal of southern coastal living. Just a short 25-min...

54 Pelican Bay is a breath of fresh ocean air! Offering lagoon and pool vistas, 54 Pelican Bay features three bedrooms with three full baths and a half bath. 54 Pelican Bay is a second-row home and is brand new to family vacation units. A sizable...

**Brand New Home Completed February 2023**-614 Ocean Blvd. is Presented by Exclusive Properties Vacation Rental Agency on Isle of Palms-Ask about our Discounts!Tired of looking through tons of listings? Do you need a specific type of home or dates...

322 D Shipwatch is the ideal Isle of Palms vacation hideaway. This 2 bedroom 2 bath unit complete with an oceanfront balcony makes this an memorable time to gather with family or friends.What is really spectacular about 322 D Shipwatch is the...

Welcome to 45 Pelican Bay by AvantStay!Step into the casual rhythm of coastal living at 45 Pelican Reach, a attractively modernized getaway tucked within the gated Wild Dunes Resort on Isle of Palms. Just a short walk to the beach and moments from...

Come savor a ideal beach getaway at "The Ruffled Pelican", a 4 bedroom home centrally located on the Isle of Palms!The home, which is shaded by handsome old oak trees, is attractively located along 20th Avenue, just a short walk over the 21st Avenue...

310C Oceanside Villa is a delightful 2 bed 2 bath condo just across the street from the beach and includes a private balcony with peaks of the ocean! Located on Isle of Palm's main strip with restaurant and stores just steps away. Comes with access...

Welcome to Casa Margarita!**904 Ocean Blvd. Presented by Exclusive Properties Vacation Rental Agency on Isle of Palms***Plug in your dates to see the full quote! Email us with any questions regarding the home or the quote or discounts. NOTE: Prices...

Welcome to your dream beach vacation rental on the Isle of Palms! Located at 4403 Palm Boulevard, this gorgeously refreshed 4-bedroom, 4.5-bath Southern-style home is appealingly located just 500 feet—or one short block—from the pristine...

Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of Palms. We specialize in gorgeous, luxury or budget friendly vacation...

Keywords: Custom Home, Cavernous, Beach House, Secluded Neighborhood, Isle of Palms, 4 bedrooms, WIFIThis enchanting beach home is located just outside Charleston, South Carolina on the fashionable Isle of Palms. Our vacation home is huge with an...

Welcome to 313 Seascape by AvantStay, your ocean-view escape located within the gated Wild Dunes Resort on Isle of Palms. Perched on the third floor of Seascape Villas, this condo puts you steps from the beach and a world away from the everyday —...

New Listing! Incredible 180 degree vistas of Wild Dunes salt marsh landscape. 34 Marsh IslandTucked at the end of a calming cul-de-sac, this inviting home is an ideal getaway for nature lovers seeking a peaceful escape.Inside, you'll find a...