Isle of Palms, SC 2+ Bedroom Vacation Rentals

Beachwood West 6 by Wild Dunes5 Bedrooms | 3.5 Bathrooms | Sleeps 12 | Resort View________________________________________Welcome to Beachwood West 6, a impressive getaway on Isle of Palms’ exclusive Wild Dunes Resort. Located in the exclusive...

Welcome to Sand Dune. Heaven beckons from this exceptional beach home that's located only 1 block away from the sandy shores of Isle of Palms Beach. Recently refreshed in 2025, Sand Dune now features major upgrades to the kitchen and bathrooms...

Welcome to 312 B Shipwatch! This gorgeously designed 3BDR condo is highlighted with a amazing oceanfront balcony, beach access, and a community pool! The interior of 312 B Shipwatch welcomes you with an open floor plan and impressive coastal decor...

Step inside 37 Ocean Point. A luxury five bedroom, five bathroom home in the Ocean Point neighborhood of the Wild Dunes community. Located at the very end of Wild Dunes, Ocean Point is highly sought-after due to its privacy, striking and broad...

Gather your family together and treat them to a dream vacation at 29 on 24th Avenue on the Isle of Palms. This four-bedroom, three bath home has the amenities that will make everybody’s dreams come true. The kids will run straight to the new pool...

Discover the allure of coastal living at 118 Seascape, a two-bedroom beachfront haven located in the Seascape Condominium complex. This inviting getaway combines seamless beach access with the convenience of a community swimming pool, offering the...

Step into unparalleled coastal luxury at this freshly constructed, professionally designed oceanfront 5-bedroom home—one of Isle of Palms' premier vacation units. Sandcastle, 2704 Palm Blvd., has every detail crafted for high-end living, from the...

Welcome to 2905 Palm Boulevard! Located on the beautiful ocean-side of the Isle of Palms, a classic beach town near historic Charleston, South Carolina, this gorgeous home was FULLY REBUILT IN 2024 and expanded to 6 roomy bedrooms - all with...

Welcome to 9 22nd Avenue, a impressive luxury getaway on the Isle of Palms where casual coastal living meets high-end design. Just steps from the sand, this six-bedroom, four-and-a-half-bath home offers the ideal balance of sophistication and...

Lagoon Villa 14 by Wild Dunes2 Bedrooms | 2 Bathrooms | Sleeps 6 | Resort View________________________________________Set alongside a relaxing lagoon, this 1218 Sq. Ft. Lagoon Villas home provides a peaceful coastal getaway with access to a complex...

Check your cares at the door and settle into vacation mode at this pretty Isle of Palms hideaway! Located just two blocks from the beach and only steps from the eateries and amenities of Wild Dunes Resort, this home really offers the best of both...

Bikinis and MartinisLocation: Isle of Palms, SCOverview:Welcome to Bikinis and Martinis, a gorgeous 5-bedroom, 5.5-bathroom new construction home located just a block from the beach on Isle of Palms. This luxury getaway offers an open-concept design...

Welcome to Sawyer, an AvantStay home! Located on the handsome beachy Isle of Palms just 30 mins. away from downtown Charleston, this home is a fabulous getaway for those looking for a calming spot a ideal distance from the action. Cook up some fresh...

Camp Carolina has a private pool and is close to the beach and Downtown Isle of Palms. This home is located on Carolina Blvd and is in a location which accepts for walking to the beach, eateries, live music and stores. The beach path is only a 2...

$200 gift card for WEEK stays!Qualifying weeks are - June 20-27th, July 4-11th, July 25-Aug 1509 Summerhouse Villa, a attractively appointed 2-bedroom, under new ownership and management! A 2-bathroom villa perched on the fifth floor of the...

Links Clubhouse 15 by Wild Dunes2 Bedrooms | 2.5 Bathrooms | Sleeps 6 | Resort View________________________________________Just a 6 min. walk from the pristine beach and the elegant Links Golf Course, this 1300 Sq. Ft. elegantly appointed getaway...

Welcome to 36 Grandiose Pavilion, a beautiful coastal getaway ideally located in the heart of Wild Dunes Resort. This elegantly appointed home offers the best of Isle of Palms living, just steps from the beach and moments from the resort's most...

The Graybrooke House – Unparalleled Vistas, Elegant Design & Private PoolWelcome to The Graybrooke House, where sweeping coastal vistas, modern luxury, and impeccable design converge. This 6-bedroom, 6 full + 2 half bath Isle of Palms getaway...