Isle of Palms, SC 6+ Bedroom Vacation Rentals

*During Summer months this home books Friday to Friday**Plug in your dates to see the full quote! Email us with any questions regarding the home or the quote. --Description--New to our Luxury Collection, 'Serenity- 2 50th Ave." is a freshly...

** During the summer we book Saturday to Saturday. Off-season we require a 3 nighttime minimum **-- Description --'Villa del Mare' is an ocean view Mediterranean masterpiece and is located just a few steps from the beach. On the relaxing Isle of...

Sandy CheeksLocation: 6 26th Ave Isle of Palms, SCOverview:Welcome to this entirely refreshed 6-bedroom, 3-bathroom home on the elite Isle of Palms. Ideal for families or groups, this roomy single-family home offers opulent amenities, including a...

Ask about our Spring/Summer 2026 discounts! **This home books Friday to Friday in the Summer months**--Description--Part of our luxury collection, 'Villa Las Palmas', 206 Ocean Blvd., is a seven bedroom, seven and a half bathroom oceanfront home...

Step into the epitome of luxury and relaxation at 7 Beachwood East, a freshly constructed modern beach home located in a gated community just one lot back from the ocean. Ideal for family get-togethers or group getaways, this 7-bedroom masterpiece...

Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of Palms. We specialize in handsome, luxury or budget friendly vacation...

**We are Saturday to Saturday in the Summer, but we have a 3 nighttime min in the off-season**--Description--'Seascapes' 714 Ocean Blvd, is a classic oceanfront home located in the esteemed Ocean Blvd. side of the island which places the beach just...

Welcome to your Isle of Palms escape at 3806 Cameron Boulevard—a impressive 6-bedroom coastal getaway designed for memorable beach vacations with family and friends.Located on the 3rd row of homes on the island and just steps from the sand, this...

** During the summer we book Friday to Friday. Off-season we require a 3 nighttime minimum **--Description--'Coastal Manor' is a brand new bespoke constructed home located on Palm Blvd. right across from the ocean with a convenient beach access just...

Beachwood East 19 by Wild Dunes7 Bedroom | 7 Bathroom | Sleeps 16 | Oceanfront _____________________________________Welcome to Beachwood East 19, a striking getaway on Isle of Palms’ exclusive Wild Dunes Resort. Feel island living in this gorgeous...

One row back from the beach! This ocean view, 9 bedroom 6 and a half bath home is loaded with amenities for your family getaway. Charm and coastal style are found throughout this striking vacation home which has an in ground pool, huge yard with...

Nostos~ 6 51st Ave presented by Exclusive Properties on Isle of Palms. Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of...

The Graybrooke House – Unparalleled Vistas, Elegant Design & Private PoolWelcome to The Graybrooke House, where sweeping coastal vistas, modern luxury, and impeccable design converge. This 6-bedroom, 6 full + 2 half bath Isle of Palms getaway...

**Summer bookings are Sat. to Sat. We have a 3 nighttime min in the off-season** Description"Isle be Back" - 5 57th Avenue is one of our newest additions. It is a handsome, six bedroom, five and a half bathroom inverted floor plan home with...

Welcome to 2905 Palm Boulevard! Located on the charming ocean-side of the Isle of Palms, a classic beach town near historic Charleston, South Carolina, this gorgeous home was FULLY REBUILT IN 2024 and expanded to 6 roomy bedrooms - all with ensuite...

Welcome to 3 47th Avenue, where striking architecture meets modern design. This roomy getaway invites you to indulge in the ideal blend of luxury and comfort.Marvel at the unique private pool, boasting an in-water sitting area for unparalleled...

COMPLIMENTARY Pool Heating! 4+ nighttime stays through 2/15/27 with code COZY2807. New reservations only; restrictions apply.Introducing THE PEARL, one of our premier properties on the Isle of Palms! This cavernous Charleston-style home was...

This beautiful 6 bedroom, 6.5 bathroom home is ready to welcome you for a once-in-a-lifetime beach escape. Just one block to the beach, it has all you need to make excellent memories on the Isle of Palms. It features two living rooms, a completely...