Isle of Palms, SC 4+ Bedroom Vacation Rentals

Welcome to 3602 Cameron, where beachside living meets modern elegance. Located in the heart of the Isle of Palms, this impressive getaway is just steps from pristine sandy shores, offering the ideal blend of relaxation and convenience. Whether...

Make everlasting memories with you and your whole family on your next vacation at 808 Ocean Boulevard. 808 Ocean Boulevard is a impressive private 6 bedroom 6 bath home located oceanfront on the southern side of the Isle of Palms. Just mins. walk...

Monthly Winter Rental Pricing, stays 28+ nights, please inquire! Welcome to 910 Ocean Boulevard! This oceanfront getaway has something for the entire family. Choose your favorite spot from multiple oceanfront decks, poolside, calming in the hot tub...

Why keep dreaming of a excellent family vacation, when you can visit this striking condominium oceanfront in the heart of Isle of Palms? “Ocean Palms” has the best of everything when it comes to a dreamy trip to the island. The sizable...

Welcome to your idyllic hideaway at 302 Charleston Blvd on the enchanting Isle of Palms, SC! This elegant vacation rental home offers five bedrooms and three and a half baths, ensuring ample space for relaxation and recreation. A highlight of this...

Located the exclusive Yacht Harbor area of Wild Dunes Resort on the Isle of Palms, this enchanting 4 bedroom, 4.5 bathroom provides the ideal island hideaway. With private pool, golf course vistas, and a short walk to the IOP Marina, it's a...

Boardwalk at Grandiose Pavilion 128 by Wild Dunes4 Bedrooms | 4 Bathrooms | Sleeps 10 | Resort View________________________________________Boardwalk at Grand Pavilion features colorful townhomes centrally located along the spectacular beach...

This splendid 6 bedroom/6 bathroom home is located in an ideal location on the island: one block from the ocean with a direct beach access path, a short distance to the IOP Marina, and walking distance to the Citadel beach home. The peaceful...

Vacation in style and live like royals when you book our cavernous and extravagant 609 Ocean Blvd beach home at Isle of Palms. Stay right opposite the ocean at one of the best spots in the area and spend a memorable time with your appreciated ones...

** During the summer we book Saturday to Saturday. Off-season we require a 3 nighttime minimum **--Description--As part of our Island Collection, 'Pavilion a la Plage' 4 10th Ave, is a seven bedroom, five and a half bathroom home located in the...

Casa TortugaLocation: Isle of Palms, South CarolinaOverview:Welcome to Casa Tortuga, a extravagant 5-bedroom, 5.5-bathroom island getaway designed for the ultimate family vacation. Located on the impressive Isle of Palms, this modern home features a...

Ask about our Summer 2026 discounts!! *During Summer months this home books Friday to Friday**Plug in your dates to see the full quote! Email us with any questions regarding the home or the quote. --Description--New to our Luxury Collection...

You will think you found the ideal vacation when you discover "Oceanside Serenity" at 203 Ocean Palms on the Front Beach at the Isle of Palms. This is an oceanfront, four-bedroom, four-bath condominium with 2,000 square feet of living space...

Tucked away under old oak trees located on roughly an acre site, this beautiful home is nothing short of a coastal getaway. Inside you will find coastal decor throughout this 4 bedroom 3 bath home. This home features combination kitchen/living room...

Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of Palms. We specialize in handsome, luxury or budget friendly vacation...

Exquisitely Decorated Modern House on a Quiet Street and 5 Min Walk to the Beach!Property HighlightsThree min. walk to the beachStunning updates and renovationsRoomy family homeChefs kitchenBooks, Toys and GamesThis is not your average vacation...

Escape to Global Elegance: A Coastal Sanctuary at 6 31st Avenue!Property HighlightsSizable Private Pool A few mins. walk to the beachChefs KitchenElevator$250 Beach Gear Credit with 3-14 nighttime stays!Note- All TVs are streaming only so please...

Located in the heart of Wild Dunes Resort and just steps from the Atlantic Ocean, this special oceanfront home is the ideal spot for an Isle of Palms vacation! This gem is a 4 bedroom, 4 bathroom home located directly on the fashionable Grandiose...