Isle of Palms, SC 4+ Bedroom Vacation Rentals

Gather your family together and treat them to a dream vacation at 29 on 24th Avenue on the Isle of Palms. This four-bedroom, three bath home has the amenities that will make everybody’s dreams come true. The kids will run straight to the new pool...

NEW SWEETGRASS LISTING FOR 2025! Escape to this impressive 5-bedroom, 4-bathroom beach home, ideally located just two blocks from the pristine Isle of Palms beach. Designed for relaxation and entertainment, this home features a private pool and hot...

7 Fairway Oaks is a elegant Vacation Home located in Wild Dunes. Beach Access straight across the street (Only 135 yards to the beach!). Features an open floor plan, 4 Bedrooms, 4 and 1 half baths in over 3400 sqft with tons of space for a huge...

Sun, sand, and wellness collide at Stay Salty—a brand-new, oceanfront getaway on Isle of Palms where modern luxury meets intentional, healthy living. With six bedrooms (including 5 California King beds), six full bathrooms, and a powder room, this...

2207 Cameron Blvd is just a stone's throw away from the best Isle of Palms has to offer. Beach access is a breeze from this corner lot which is only one block from the ocean. Local eateries, bars, groceries, and coffee stores are just 4 blocks to...

Ask manager for current Summer Discounts! --Description--'Heaven Palms' -3803 Palm Blvd, is a brand new, bespoke constructed home presented by Exclusive Properties with open spaces, architectural details and windows galore with spectacular ocean...

The Rosemary House – Modern Elegance Meets Island CharmWelcome to The Rosemary House, a chic and sun-soaked getaway located just behind the gates of Wild Dunes Resort and mere steps from the pristine sands of Isle of Palms. This newly constructed...

Sunshine, we’ve got it! Now all we must add is you and your family to this much sought-after vacation hideaway, 125 Grandiose Pavilion! Conveniently located in the Grandiose Pavilion Community in Wild Dunes, this amazing home is near eateries, a...

Welcome to Casa Flamingo! Presented by Exclusive Properties on Isle of Palms. *Plug in your dates to see the full quote! Email us with any questions regarding the home or the quote or discounts. **Available all year! During the Summer months...

Welcome to 302 Summerhouse, a 4-bedroom 4-bath oceanfront condo with spectacular vistas of the Atlantic Ocean. Parlor on the huge, covered balcony watching the waves. This floor plan includes a roomy living room and outfitted kitchen with plenty of...

Welcome to Derby, an AvantStay home!Beachy, sophisticated, and fun in every way, this oceanfront home is ideal for sizable groups looking to get away somewhere warm. With soft, plush furnishings and natural light that pours in through huge windows...

Located at #9 on 24th Avenue, this beach home features six bedrooms, six full baths, and two half baths. A beach path at the end of the block makes walking to the surf simple for the entire family, where they will find one of the best stretches of...

311 Carolina Boulevard is really a rare find with ocean vistas, private pool, four roomy decks, and magnificant amenities to meet your every vacation wish. Step into your vacation dream that features five bedrooms, each with a king bed, four full...

Luxury, Leisure, and Pickleball—All Just Steps from the Sand*New property for Sweetgrass. 25+ previous 5-star reviews.If you're looking for a standout luxury beach rental on Isle of Palms, welcome to your dream vacation home. 3903 Cameron...

5 32nd Avenue, is the ideal heading to lead you to the ideal beach vacation on the Isle of Palms at 5 on 32nd Avenue. This striking home is modeled in a nautical theme, straight from a 1920’s racing sailing schooner. Heart of Pine floors, white...

Welcome to Palmetto, an AvantStay home!There are so many reasons you’ll adore it here. For starters, this lush home is just steps from the clear blue waters of Isle of Palm’s beach. But you may be tempted to spend your days swimming in the pool...

Get ready for an impressive and fun-filled beach vacation when you select charming accommodation for your stay. At Carroll Realty, we are excited to tell you about this cavernous vacation home located right by the ocean. Walk a few steps to savor...

White SandsLocation: Isle of Palms, South CarolinaOverview:Welcome to White Sands, a gorgeously remodeled 4-bedroom, 4.5-bathroom coastal getaway on Palm Boulevard. Professionally designed with high-end finishes, this handsome home offers luxury...